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My WMCC
Clinical Trials: Ongoing Trials

Genitourinary System

PSA = Prostatic Specific Antigen

GS = Gleason Score

TNM Staging: T = Tumor, N = Nodal status, M = Metastasis

Site

Stage/Description

Protocol Title

Bladder

Muscle invasive, non-cystectomy candidates

RTOG 0524: Paclitaxel and trastuxumab with daily RT versus Paclitaxel alone with daily RT followed by transurethral surgery

Renal Insufficiency MDA 2005-0839: Gemcitabine, paclitaxel & Doxorubicin with Pegfilgrastim
Testicular   None
Ureter or Urethra Advanced and prior treatment None
Prostate

Localized, high risk with the one of the following:

GS>/=9 / PSA </=150 / any T GS 8 / PSA < 20 / > / = T 2 GS7-8 / PSA>/=20-150/Any T

RTOG 0521: Hormone suppression plus 3D Intense Modulated RadiationTherapy (IMRT) versus Hormone suppression plus 3D Intense Modulated Radiation Therapy (IMRT) followed by Doxetaxel and Prednisone.

T1c - T2b

GS 2 - 6 and PSA > / = 10

or

GS < 7 and PSA 10-20

or

GS 7 and PSA < 10

RTOG 0232: External Radiation Therapy with Brachytherapy versus Brachytherapy alone
Rising PSA

RTOG 0534: Transperineal ultrasound guided brachytherapy following external beam radiotherapy

RTOG 0622: Samarium 153 the Radiation therapy after radical prostatectomy (Presently on Hold)

Locally Recurrent RTOG 0526: Transperineal ultrasound guided brachytherapy following external beam readiotherapy
Stage D2 None
Extensive Disease

ECOG E3805 (CHAARTED): ChemoHormonal Therapy versus Hormonal Therapy Ablation

ECOG E5805: Halichondrin B analog (E7389) for hormone refractory

Hormone refractory

CTSU S0421: Docetaxel & Astrasentan versus Docetaxel & Placebo

MDA ID00-156: Adriamycin/Ketoconazole alternating with Vinblastine / Estramustine OR Taxol / Estramustine with or without SR-89 plus 6 weeks of Adriamycin

ECOG E3803: BMS 247550--Must have received prior treatment with Taxane

ECOG E5805: Halichondrin B analog (E7389) for hormone refractory

Renal No Prior Treatment

ECOG E4805: Two different doses of AVE0005 (VEGF Trap)--must have had ONLY one prior treatment with either Sutent or Nexavar for at least 12 weeks

ECOG E2805: Adjuvant Sunitinib versus Sorafenib versus Placebo

ECOG E2804 (BEST): VEGF, RAF Kinase & mTOR combo, targeted therapy with Bevacizumab + Sorafenib + Temsirolimus

 


West Michigan Cancer Center • 200 North Park Street • Kalamazoo, MI 49007 • 269-382-2500