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Clinical Trials: Ongoing Trials

Gynecologic

Site

Stage/Description

Protocol Title

CervixTreated with radical hysterectomy / lymph node dissection None

 

 

No prior treatment, limited to the pelvis: Stage IB2, IIA, IIB, IIIB, IVA

None

One prior treatment (performance status 0 -2)

GOG 127V: ABI-007 (Suspended)

Pelvic / para-aortic lymphademectomy GOG 221: Glycoprotein & Glycan profiling
Persistent or Recurrent GOG 0227E: Cetuximab
Vulvar Malignancies Locally advanced and squamous cell

GOG 205: Radiation therpay and weekly Cisplatin

GOG 0173: Intraoperative lymphatic mapping & Sentinel node identification

Ovary Bone Mineral Denisty GOG 215: Zoledronic acid versus observation for women who have risk reducing surgery that removed both ovaries
Recurrent and Platinum sensitive GOG 213: Carboplatin and Paclitaxel versus Carboplatin, Paclitaxel and Bevacizumab, followed by Bevacizumab and cytoreductive surgery
Recurrent and Platinum resistant GOG 0126R: Abraxane
Stromal tumors GOG 187: Paclitaxel as second line therapy
Cancer of the Fallopian Tube Biochemical (Rising CA-125) recurrence only NONE
Recurrent and Platinum sensitive GOG 213: Carboplatin and Paclitaxel versus Carboplatin, Paclitaxel and Bevacizumab, followed by Bevacizumab and cytoreductive surgery
Recurrent and Platinum resistant GOG 0126R: Abraxane
Epithelial Ovarian/ Primary Peritoneal cancer

Biochemical (Rising CA-125) Recurrence Only

NONE

Suboptimal, residual disease--Stage III / IV GOG 0218: Carboplatin and Paclitaxel with Bevacizumab versus Carboplatin and Paclitaxel with Placebo
Complete response to primary Platinum / Taxane Chemotherapy GOG 0212: Paclitaxel once every 4 weeks for 12 treatments versus Xyotax once every 4 weeks X 12 treatment versus no further treatment
Recurrent and Platinum sensitive

GOG 213: Carboplatin and Paclitaxel versus Carboplatin, Paclitaxel and Bevacizumab, followed by Bevacizumab and cytoreductive surgery

Recurrent and Platinum resistant GOG 0126R: Abraxane
Persistent/Recurrent

GOG 170M: Dasatinib

EndometrialStage IB (Grade 3), Stage IC (Grade 1-3), Stage IIA or IIB None
 

Stage III/IV

GOG 0209: Doxorubicin / Cisplatinum / Paclitaxel / G-CSF versus Carboplatin / Paclitaxel

GOG 232C: Paclitaxel, Carboplatin and BSI-201

Recurrent / Persistent Disease

No prior treatment

GOG 0209: Doxorubicin / Cisplatinum / Paclitaxel / G-CSF versus Carboplatin / Paclitaxel

GOG 232C: Paclitaxel, Carboplatin and BSI-201

  Any number of prior treatments

GOG 188 Faslodex

Carcinosarcoma No prior treatment NONE
Prior treatments NONE
Leiomyosarcoma No prior treatments NONE
Prior treatments GOG 87M: Trabectedin Suspended


West Michigan Cancer Center • 200 North Park Street • Kalamazoo, MI 49007 • 269-382-2500